The biodiversity of Actinomycetes in the River Nile exhibiting antifungal activity

The taxonomic analysis of 114 actinomycete strains isolated from water of the River Nile and its bottom sediments showed that most of the water isolates belonging the genus Streptomyces. As well as, the majoring of the sediment isolates belongs to the genus Micromonospora. The overwhelming majority of Streptomyces species are Str. antibioticus, Str. aunlatus, Str. violaceus and Str. antimycoticus. M. carbonaceae and M. purpureochromogenes were also identified. Of 68 Streptomyces strains obtained, 11-exhibited significant antimycotic activity. Among the test fungi examined, Aspergillus niger and Trichoderma viride proved to be the most susceptible to the active substance present in the fermentation broths of Streptmyces strains. These active substances seem to be polyenes. its bottom sediments at Giza and Cairo and examinating the antimycotic activities of streptomycete isolates. Material and methods